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Both: may increase weekly by 5–10mg/kg per day; max 60mg/kg per day; give in divided doses if total daily dose >250mg. Efficacy reduced by rifampin, phenytoin, carbamazepine, phenobarbital, carbapenems, estrogen-containing hormonal contraceptives; monitor serum valproate concentrations. Elderly: reduce initial dose and titrate slowly; monitor. Pharmacology, adverse reactions, warnings and side effects. for 1Monitor levels of valproate, ethosuximide, other anticonvulsants, and whenever an enzyme inducer is added or withdrawn. Menstruation. By selecting "Yes" below, you certify that you are a Healthcare Professional and that you wish to proceed to the Healthcare Professionals Only section of this site. Concomitant topiramate may cause hyperammonemic encephalopathy, hypothermia. Do not start or stop other medicines without talking to your healthcare provider.DEPAKOTE can cause other serious side effects, including:You are encouraged to report negative side effects of prescription drugs to the FDA. Others: see full labeling.Abdominal pain, accidental injury, alopecia, ambylopia/blurred vision, amnesia, anorexia, asthenia, ataxia, back pain, bronchitis, constipation, depression, diarrhea, diplopia, dizziness, dyspepsia, dyspnea, ecchymosis, emotional lability, fever, flu syndrome, headache, increased appetite, infection, insomnia, nausea, nervousness, nystagmus, peripheral edema, pharyngitis, rash, rhinitis, somnolence, abnormal thinking, thrombocytopenia, tinnitus, tremor, vomiting, weight gain, weight loss; hepatotoxicity, structural birth defects, acute pancreatitis, hyperammonemia, hypothermia.Tabs 125mg—100; Tabs 250mg, 500mg—100, 500; ER 250mg—100; ER 500mg—100, 500Not for treating women with epilepsy or bipolar disorder during pregnancy or plan to become pregnant unless other alternatives failed to provide adequate control or are otherwise unacceptable.≥18yrs: initially 750mg daily in divided doses; max 60mg/kg per day. Depakote (divalproex sodium): “I was prescribed Depakote ER 500mg to help my anxiety and it has decreased my anxiety 90%. (divalproex sodium) delayed-release tablets, for oral use(divalproex sodium delayed release capsules), for oral useDEPAKOTE can cause serious side effects, including:Before taking DEPAKOTE, tell your healthcare provider if you:Taking DEPAKOTE with certain other medicines, even for a short period of time, can cause side effects or affect how well they work.
Migraine prophylaxis in pregnant women and women of childbearing potential not using effective contraception.Life-threatening adverse reactions (eg, hepatotoxicity, fetal risk, pancreatitis). Antidepressants.
Elderly: reduce initial dose and titrate slowly; monitor. 1 2.
in children <2yrs of age. Increased risk of hepatotoxicity in patients with congenital metabolic disorders, multiple AEDs, severe seizure disorders with mental retardation, organic brain disorders, mitochondrial disorders, esp. CNS depression with alcohol, other CNS depressants. Home Science Math History Literature Technology Health Law Business All Topics Random. AbbVie is not responsible for the contents of any such site or any further links from such site. Potentiates carbamazepine, diazepam, ethosuximide, lamotrigine, phenobarbital, phenytoin, tolbutamide, warfarin, zidovudine, amitriptyline, nortriptyline, propofol, rufinamide. Discontinue if hepatic dysfunction, pancreatitis, thrombocytopenia, hyperammonemia, hypothermia, or DRESS/multi-organ hypersensitivity reactions occur. in children <2yrs of age. You should also be aware that the linked site may be governed by its own set of terms and conditions and privacy policy for which AbbVie has no responsibility.Conversely, the presence of this link does not imply the linked site’s endorsement of Depakote.com or AbbVie.Health insurance that you or a family member obtained through an employer or purchased privatelyState or federally funded insurance programs such as Medicare (including Part D), Medicare Advantage, Medigap, Medicaid, TRICARE, Department of Defense, or Veterans Affairs The DEPAKOTE Savings Card is not available to individuals who are paying cash for their prescription or who are receiving prescription reimbursement under a state or federally funded insurance program.This rebate form is not available to individuals who are paying cash for their prescription or who are receiving prescription reimbursement under a state or federally funded insurance program.©2020 AbbVie Inc. North Chicago, IL 60064 US-DPKT-200005 July 2020
Potentiates carbamazepine, diazepam, ethosuximide, lamotrigine, phenobarbital, phenytoin, tolbutamide, warfarin, zidovudine, amitriptyline, nortriptyline, propofol, rufinamide. Uses: Depakote is prescribed for Bipolar Disorder, Seizures, Mania and Epilepsy and is mostly mentioned together with these indications. Please talk to your doctor for more information on seizure first aid. DEPAKOTE can cause serious side effects, including: Serious liver damage that can cause death, especially in children younger than 2 years old. Concomitant topiramate may cause hyperammonemic encephalopathy, hypothermia.
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