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New York: Ardent Media, 1998:435Side Effects Related to the Estrogen or Progestin Component of Oral Contraceptive Pills*Adapted with permission from Hatcher RA, Trussel J, Stewart F, Cates W Jr, Stewart GK, Guest F, et al. Chart of FDA-approved and cleared methods for birth control. Additional contraception is used for the remainder of the cycle.The patient uses an additional contraceptive method for the first 7 days after initially starting oral contraceptive pills.The patient uses an additional contraceptive method for 7 days if she is more than 12 hours late in taking an oral contraceptive pill.The patient uses an additional contraceptive method while she is taking an interacting drug (see The patient begins taking the pills on the first day of menstrual bleeding.The patient begins taking the pills on the first Sunday after menstrual bleeding begins.The patient begins taking the pills immediately if she is definitely not pregnant and has not had unprotected sex since her last menstrual period.If it has been less than 24 hours since the last pill was taken, the patient takes a pill right away and then returns to normal pill-taking routine.If it has been 24 hours since the last pill was taken, the patient takes both the missed pill and the next scheduled pill at the same time.If it has been more than 24 hours since the last pill was taken (i.e., two or more missed pills), the patient takes the last pill that was missed, throws out the other missed pills and takes the next pill on time.

Instructions on the use of oral contraceptive pills are provided in The patient begins taking the pills on the first day of menstrual bleeding.The patient begins taking the pills on the first Sunday after menstrual bleeding begins.The patient begins taking the pills immediately if she is definitely not pregnant and has not had unprotected sex since her last menstrual period.If it has been less than 24 hours since the last pill was taken, the patient takes a pill right away and then returns to normal pill-taking routine.If it has been 24 hours since the last pill was taken, the patient takes both the missed pill and the next scheduled pill at the same time.If it has been more than 24 hours since the last pill was taken (i.e., two or more missed pills), the patient takes the last pill that was missed, throws out the other missed pills and takes the next pill on time.

Carr BR,

Estrogen replacement therapy is helpful for treating menopausal symptoms and preventing osteoporosis.

A quadriphasic combined oral contraceptive pill that contains oestradiol valerate and desogestrel is formulated with an oestrogen step-down and progestogen step-up sequence.The pill is a user-dependent method. Therefore, the family physician needs to provide thorough counseling before this form of contraception is initiated and should be prepared to respond to complaints after a teenage girl starts taking the pill.No evidence exists that epiphyses close prematurely in very young oral contraceptive pill users, and bone density is well preserved.The American Academy of Family Physicians has published a policy position statement regarding contraceptive advice in adolescents.The use of “emergency” contraception in the first 72 hours after unprotected sexual intercourse has been studied for almost two decades. drospirenone)Extended pill regimen to reduce the frequency of bleedingNo evidence supports a benefit of one type of oral contraceptive pill over anotherIf taking an ethinyloestradiol 20 microgram pill, increase oestrogen dose to a maximum of 35 microgramCombined oral contraceptive pills are associated with an increase in the risk of myocardial infarction and ischaemic stroke. Kaplan B. Retrospective case studies indicate a weak association between ampicillin, amoxicillin, metronidazole (Flagyl) and tetracycline and ineffectiveness of oral contraceptive pills.

The risk of venous thromboembolism appears to vary with oestrogen dose and progestogen type.

The combination of oral contraceptive pill use and smoking has a greater effect on risk than the simple addition of the two factors.

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