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June 1, 2018 DIABETES Ozempic Victoza April 1, 2018 DIABETES QTERN January 1, 2018 MISCELLANEOUS Nityr+ STANDARD (CIGNA NATIONAL) PRESCRIPTION DRUG LIST (cont) Start date of change* ... 1%, Voltaren PAIN RELIEF AND INFLAMMATORY DISEASE (NARCOTIC) acetaminophen-caffeine-dihyrocodeine, acetaminophen-codeine, Arymo, asa-butalb- The doctor must make an application to the Exception Drug Status office. 2010 Alberta College of Pharmacy. If your husband has the eye disease diabetic retinopathy, using Ozempic might make it worse. voltaren-ophthalmic-diclofenac-ophthalmic-343643 The innoviCares card can be used with an existing drug plan (private or public) or on its own.

Data sources include IBM Watson Micromedex (updated 2 Sep 2020), Cerner Multum™ (updated 1 Sep 2020), … Some drug products not listed on the Formulary are reimbursed through the Exceptional Access Program (EAP). Drugs

Contact the applicable plan There are two ways you can receive reimbursement on your prescription with innoviCares: provider for the most current information.The recipient will receive more details and instructions to access this offer.By clicking send, you acknowledge that you have permission to email the recipient with this information.The recipient will receive more details and instructions to access this offer.By clicking send, you acknowledge that you have permission to email the recipient with this information.

If you log out, you will be required to enter your username and password the next time you visit. Oral solution: Do not use liquids other than water to reconstitute; foods decrease effectiveness. Diclofenac sodium: Voltaren XR. Extended release: 100 mg PO once daily; may be increased to 100 mg PO q12hrExtended release: 100 mg PO once daily; may be increased to 100 mg PO q12hrImmediate-release (Cataflam): 100 mg PO once, then 50 mg PO q8hr PRNImmediate-release tab (Cataflam): 100 mg PO once, then 50 mg PO q8hr PRNIndicated for management of mild-to-moderate pain and moderate-to-severe pain alone or in combination with opioid analgesicsUse for the shortest duration consistent with individual patient treatment goals37.5 mg IV bolus injection infused over 15 seconds q6hr as needed, not to exceed 150 mg/dayTo reduce the risk of renal adverse reactions, patients must be well hydrated prior to IV administrationOral solution: 50 mg (1 packet) in 30-60 mL of water, mixed well and drunk immediatelyTake with food or 8-12 oz of water to avoid GI adverse effectsZorvolex: Take on empty stomach; food decreases AUC by 11% and peak concentration by 60%Oral solution: Do not use liquids other than water to reconstitute; foods decrease effectivenessSafety and efficacy not established; drug has been used safely in limited number of children aged 3-16 years with juvenile rheumatoid arthritisAbsolute: Hypersensitivity to diclofenac, history of aspirin triad, treatment of perioperative pain associated with CABG; active gastrointestinal bleedingIV: Moderate-to severe renal insufficiency in the perioperative period and patients who are at risk for volume depletionZipsor capsules are contraindicated in patients with history of hypersensitivity to bovine proteinUse caution in patients with bronchospasm, cardiac disease, CHF, hepatic porphyria, hypertension, fluid retention, severe renal impairment, smoking, systemic lupus erythematosusPlatelet aggregation and adhesion may be decreased; may prolong bleeding timeUse caution in blood dyscrasias or bone marrow depression; also with thrombocytopenia, agranulocytosis, and aplastic anemia Long-term administration of NSAIDs may result in renal papillary necrosis and other renal injury; patients at greatest risk include elderly individuals, those with impaired renal function, hypovolemia, heart failure, liver dysfunction, or salt depletion, and those taking diuretics, angiotensin-converting enzyme inhibitors, or angiotensin-receptor blockersTherapy may increase risk of hyperkalemia, especially in renal disease, diabetics, the elderly, and concomitant use of agents that may induce hyperkalemia; monitor potassium closelyMay cause dizziness blurred vision and neurologic effects that may impair physical and mental abilitiesRisk of serious skin reactions, including Stevens Johnson syndrome and necrotizing enterocolitisPersistent urinary symptoms, including bladder pain and dysuria, hematuria or cystitis may occur after initiating therapy; discontinue therapy with symptom onset and evaluate causeIncrease in transaminase levels reported within 2 months of therapy; may occur at any time; monitor transaminase levels periodically beginning 4-8 weeks after initiation of therapyMay increase risk of aseptic meningitis (rare), especially in patients with systemic lupus erythrmatosus, and mixed connective tissue disordersUse caution if patient dehydrated before initiating therapy; rehydrate patient before initiating therapy and monitor renal function closelyInjectable dosage form not recommended for long-term useOveruse of acute migraine drugs (eg, ergotamine, triptans, opioids, nonsteroidal anti-inflammatory drugs or combination of these drugs for 10 or more days per month) may lead to exacerbation of headache (medication overuse headache); may present as migraine-like daily headaches or as a marked increase in frequency of migraine attacks; detoxification of patients, including withdrawal of overused drugs and treatment of withdrawal symptoms (which often includes a transient worsening of headache) may be necessaryDifferent formulations not bioequivalent even if milligram strength the same; do not interchange productsWithhold for at least 4-6 half-lives prior to surgical or dental proceduresPublished literature reports that use of NSAIDs after 30 weeks’ gestation increases risk of premature closure of fetal ductus arteriosus; data from observational studies regarding potential embryofetal risks of NSAID use, including diclofenac, in women in first or second trimester of pregnancy are inconclusive; avoid use of NSAIDs in pregnant women starting at 30 weeks of gestation (third trimester)Data from published literature reports with oral preparations of diclofenac indicate presence of small amounts of diclofenac in human milk; there are no data on effects on breastfed infant, or on milk production; consider developmental and health benefits of breastfeeding along with mother’s clinical need for therapy and any potential adverse effects on breastfed infant from treatment or from underlying maternal conditionA: Generally acceptable.

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