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Naeini FF, Najafian J, Ahmadpour K. Bleomycin tattooing as a promising therapeutic modality in large keloids and hypertrophic scars. Keloid. Peled ZM, Rhee SJ, Hsu M, Chang J, Krummel TM, Longaker MT. ClinicalTrials.gov. Kontochristopoulos G, Stefanaki C, Panagiotopoulos A, et al. Effects of interferon-alpha2b on keloid treatment with triamcinolone acetonide intralesional injection. The effect of narrowband ultraviolet B on the expression of matrix metalloproteinase-1, transforming growth factor-beta1 and type I collagen in human skin fibroblasts. Xiao Z, Zhang F, Cui Z. If you have a history of hypertrophic scars or keloids and require surgery, a doctor may inject steroids into the area before surgery begins. Comparison of intense pulsed light to 595-nm long-pulsed pulsed dye laser for treatment of hypertrophic surgical scars: a pilot study.
Combination of surgery and intralesional verapamil injection in the treatment of the keloid. This helps to flatten scars and reduce their appearance by controlling moisture and oxygen retention at the scar site. If you log out, you will be required to enter your username and password the next time you visit. Saray Y, Gulec AT. 2002
Lee WJ, Song SY, Roh H, Ahn HM, Na Y, Kim J, et al. mTOR as a potential therapeutic target for treatment of keloids and excessive scars. Results of a combination of bleomycin and triamcinolone acetonide in the treatment of keloids and hypertrophic scars. Postsurgical use of imiquimod 5% cream in the prevention of earlobe keloid recurrences: results of an open-label, pilot study. Steroid injections may lead to more long-term harm than previously thought, new study says. Ud-Din S, Thomas G, Morris J, Bayat A. Photodynamic therapy: an innovative approach to the treatment of keloid disease evaluated using subjective and objective non-invasive tools. Intralesional 5-fluorouracil as a treatment modality of keloids. A new uniform protocol of combined corticosteroid injections and ointment application reduces recurrence rates after surgical keloid/hypertrophic scar excision. D'Andrea F, Brongo S, Ferraro G, Baroni A. Oiso N, Kawara S, Kawada A. A novel hydrogel scaffold for the prevention or reduction of the recurrence of keloid scars postsurgical excision. Alster T. Laser scar revision: comparison study of 585-nm pulsed dye laser with and without intralesional corticosteroids. Scar-improving efficacy of avotermin administered into the wound margins of skin incisions as evaluated by a randomized, double-blind, placebo-controlled, phase II clinical trial.
ClinicalTrials.gov. Wolverton SE, ed. Pilot study of the effect of postoperative imiquimod 5% cream on the recurrence rate of excised keloids. Darougheh A, Asilian A, Shariati F. Intralesional triamcinolone alone or incombination with 5-fluorouracil for the treatment of keloid and hypertrophicscars. By Ryan Prior, CNN. Courtesy of Dirk M. Elston, MD. Nanda S, Reddy BS. Effect of recombinant human epidermal growth factor on cutaneous scar quality in thyroidectomy patients.
Without being too technical, triamcinolone (medical steroid) is an artificial compound that closely mimics the chemistry of naturally-occurring corticosteroids. ClinicalTrials.gov. Panabiere-Castaings MH. The correlation between epidermal growth factor levels in saliva and the severity of oral mucositis during oropharyngeal radiation therapy.
Aggarwal H, Saxena A, Lubana PS, Mathur RK, Jain DK. Structure of the collagen nodule from hypertrophic scars and keloids. Effect of recombinant human epidermal growth factor against cutaneous scar formation in murine full-thickness wound healing. Intralesional cryosurgery enhances the involution of recalcitrant auricular keloids: a new clinical approach supported by experimental studies. Asilian A, Darougheh A, Shariati F. New combination of triamcinolone, 5-Fluorouracil, and pulsed-dye laser for treatment of keloid and hypertrophic scars. Wittenberg GP, Fabian BG, Bogomilsky JL, et al. Berman B, Poochareon V, Villa AM.
Manca G, Pandolfi P, Gregorelli C, Cadossi M, de Terlizzi F. Treatment of keloids and hypertrophic scars with bleomycin and electroporation. Luo L, Li J, Liu H, Jian X, Zou Q, Zhao Q, et al. Berman B, Garikaparthi S, Smith E, Newburger J. If you’re considering steroid injections for your scars, continue reading before making a decision. Epstein JB, Gorsky M, Guglietta A, Le N, Sonis ST. Prevention and treatment of keloids with intralesional verapamil.
Peyton SR, Putnam AJ.
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